Glutathione from Super Human Peptides UK is a tripeptide composed of three amino acids: cysteine, glutamic acid, and glycine. Often referred to as the "Master Antioxidant," it is found in high concentrations in nearly every cell of the body. In laboratory research, Glutathione is studied for its vital role in maintaining cellular redox homeostasis and protecting organelles from oxidative damage.
Researchers utilize reduced Glutathione (GSH) to investigate the detoxification of endogenous and exogenous compounds, the regulation of the immune response, and the maintenance of mitochondrial DNA integrity. Produced under GMP-compliant conditions and verified for 99% purity or higher, this compound is a foundational tool for biochemistry and toxicology studies.
WarningFor laboratory research use only. Not for human consumption.
Key Features
- —High Purity: 99% purity or higher (verified by HPLC).
- —Reduced Form (GSH): The biologically active, electron-donating state for research.
- —Quality Standard: GMP / ISO certified manufacturing.
- —Stability: Supplied as a stable, lyophilized powder to prevent premature oxidation.
- —Documentation: Full Certificate of Analysis (COA) included.
Research Focus
- —Redox Homeostasis: Studies on the ratio of reduced (GSH) to oxidized (GSSG) glutathione as a marker of cellular stress.
- —Phase II Detoxification: Research into glutathione S-transferase (GST) enzyme activity and toxin conjugation.
- —Mitochondrial Protection: Investigating the prevention of mitochondrial membrane lipid peroxidation.
- —Cytokine Regulation: Studies on how thiol levels influence the inflammatory "inflammasome" activation.
- —DNA Synthesis and Repair: Research into glutathione's role in nucleotide metabolism and genomic stability.
Published Research and Study Findings
Scientific literature characterizes Glutathione as the primary defender against reactive oxygen species (ROS) and free radicals. Research has demonstrated that intracellular Glutathione levels are a critical determinant of cell viability; depletion of GSH is often used in laboratory models to induce apoptosis or study the progression of neurodegenerative and metabolic diseases. In animal models, Glutathione has been investigated for its ability to regenerate other antioxidants, such as Vitamin C and Vitamin E, back to their active forms.
Furthermore, studies in hepatology frequently focus on Glutathione's high concentration in the liver, examining its role in neutralizing heavy metals and environmental pollutants through mercapturic acid pathway synthesis.
NoteAll findings are derived from laboratory and non-clinical research settings.
Representative Scientific References
- 1.Meister, A. et al., "Glutathione," Annual Review of Biochemistry, 1983.
- 2.Forman, H.J. et al., "Glutathione: Overview of its protective roles, measurement, and biosynthesis," Molecular Aspects of Medicine, 2009.
- 3.Ballatori, N. et al., "Glutathione dysregulation and the etiology and progression of human diseases," Biological Chemistry, 2009.
- 4.Pizzorno, J., "Glutathione!" Integrative Medicine: A Clinician's Journal, 2014.
