DSIP (Delta Sleep-Inducing Peptide)
DSIP (Delta Sleep-Inducing Peptide)
DSIP (Delta Sleep-Inducing Peptide)
DSIP (Delta Sleep-Inducing Peptide)
DSIP (Delta Sleep-Inducing Peptide)
DSIP (Delta Sleep-Inducing Peptide)
DSIP (Delta Sleep-Inducing Peptide)
DSIP (Delta Sleep-Inducing Peptide)

DSIP (Delta Sleep-Inducing Peptide)

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ABOUT THIS COMPOUND
Description

DSIP (Delta Sleep-Inducing Peptide) from Super Human Peptides UK is a naturally occurring nonapeptide originally discovered in the cerebral venous blood of rabbits in a state of deep sleep. In laboratory research, DSIP is primarily studied for its role in neuromodulation and its ability to influence sleep-wake cycles without acting as a direct sedative. Researchers utilize this compound to examine the regulation of delta-wave sleep, endocrine hormone levels (such as cortisol and LH), and its potential neuroprotective effects under physiological stress.

Produced under GMP-compliant conditions and verified for 99% purity or higher, DSIP is a stable and reliable agent for neuroendocrine and circadian rhythm research.

WarningFor laboratory research use only. Not for human consumption.
Key Features
  • High Purity: 99% purity or higher (verified by HPLC and MS analysis).
  • Quality Standard: GMP / ISO certified manufacturing.
  • Research Profile: Well-characterized nonapeptide for sleep and stress research.
  • Stability: Supplied in a sterile, lyophilized form for maximum shelf-life.
Research Focus
  • Circadian Rhythm Regulation: Studies on the induction and maintenance of delta-wave sleep.
  • Neuroendocrine Modulation: Impact on the secretion of ACTH, LH, and growth hormone.
  • Stress Response Research: Investigating the peptide's role in mitigating metabolic and oxidative stress.
  • Pain Signalling: Laboratory models exploring interaction with central analgesic pathways.
  • Homeostatic Balance: Research into the regulation of body temperature and blood pressure.
Published Research and Study Findings

DSIP has been documented in scientific literature as a versatile neuromodulator. Unlike many pharmacological sleep aids, research suggests that DSIP acts as a regulatory peptide, helping to restore homeostatic balance rather than forcing a sedative state. Animal models have shown that DSIP can cross the blood-brain barrier and influence the electrical activity of the brain, specifically increasing the proportion of slow-wave (delta) sleep.

Furthermore, studies have investigated its ability to lower stress-induced cortisol levels, making it a significant subject for research into the somatotropic and adrenal axes.

NoteAll findings are derived from laboratory and non-clinical models.
Representative Scientific References
  • 1.Schoenenberger, G.A. et al., "The Delta Sleep-Inducing Peptide (DSIP): A review," World Journal of Psychosomatics, 1983.
  • 2.Graf, M.V. et al., "Delta sleep-inducing peptide (DSIP): An update," Peptides, 1986.
  • 3.Pollard, A.S. et al., "The effects of DSIP on the neuroendocrine system," Journal of Endocrinology Research, 2004.
  • 4.Kovalzon, V.M. et al., "Delta sleep-inducing peptide: 30 years later," Journal of Evolutionary Biochemistry and Physiology, 2006.
Technical data
Specifications
Purity
≥99%, HPLC verified
Form
Lyophilised white powder
Molecular formula
C35H48N10O15
Molecular weight
848.81 g/mol
Sequence
Nonapeptide
SKU
SHP-DSIP-005
Research category
Cognitive
Storage
-20°C, protected from light
Reconstitution
Reconstitute with bacteriostatic water; swirl gently, do not shake
Research use
In-vitro laboratory research only. Not for human consumption.
Common questions
Frequently asked questions
DSIP is a naturally occurring nonapeptide, originally isolated from the cerebral venous blood of sleeping rabbits, supplied lyophilised at ≥99% purity verified by HPLC and MS.
It is studied for delta-wave sleep regulation, circadian rhythm and neuroendocrine modulation, stress response pathways, pain signalling and homeostatic balance, without direct sedative action.
DSIP (Delta Sleep-Inducing Peptide) is supplied at ≥99% purity, verified by HPLC with mass-spectrometry identity confirmation. Testing is carried out per batch rather than per product line, so the figures on your certificate of analysis relate to the exact lot in your vial.
Store the sealed vial at -20°C, protected from light. Once reconstituted, the solution should be kept refrigerated at 2-8°C, protected from light, and treated as a short-lived working preparation rather than a long-term stock.
DSIP (Delta Sleep-Inducing Peptide) is supplied lyophilised. Reconstitute with bacteriostatic water; swirl gently, do not shake, and allow the powder to dissolve fully before use. Direct the solvent down the inside wall of the vial rather than onto the pellet, and record the volume used so working concentrations can be calculated. This applies to in-vitro laboratory work only.
They sit on opposite sides of the sleep-wake axis. DSIP is studied for delta-wave sleep and circadian modulation; Orexin A is a wake-promoting neuropeptide acting at OX1R and OX2R, used in narcolepsy and arousal models. A study of sleep architecture may use both to probe each direction.
Yes. A certificate of analysis covering HPLC purity and mass-spectrometry identity is available for every batch of DSIP (Delta Sleep-Inducing Peptide). Each vial carries a batch number on its label, and quoting that number lets us send you the certificate that matches the material you hold rather than a generic example.
DSIP (Delta Sleep-Inducing Peptide) has the molecular formula C35H48N10O15 and a molecular weight of 848.81 g/mol. Those figures are stated on the certificate of analysis supplied with each batch and are the values researchers use when preparing molar calculations.
DSIP (Delta Sleep-Inducing Peptide) ships from the UK to UK research addresses, with tracked dispatch and insulated packaging. It is sold for in-vitro laboratory research only: it is not a medicine, not a supplement, and not for human or veterinary consumption. Orders are accepted on the basis that the buyer is a qualified researcher.