Epithalon
Epithalon

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Epithalon

Epithalon
Epithalon
Epithalon
Epithalon
Epithalon
Epithalon

Epithalon

£19.00Sold out
Out of stock
Size
1
ABOUT THIS COMPOUND
Description

Epithalon (also known as Epitalon) from Super Human Peptides UK is a synthetic tetrapeptide based on a natural peptide called Epithalamin, which is produced in the pineal gland. In laboratory research, Epithalon is most notably studied for its role as a telomerase activator. Researchers utilize this compound to investigate cellular aging, telomere lengthening, and the potential for extending the replicative lifespan of human somatic cells.

Produced under GMP-compliant conditions and verified for 99% purity or higher, Epithalon provides a reliable model for studies into geroprotection and genomic integrity.

WarningFor laboratory research use only. Not for human consumption.
Key Features
  • —High Purity: 99% purity or higher (verified by HPLC and MS analysis).
  • —Telomerase Research: Primary agent for studying telomere maintenance.
  • —Quality Standard: GMP / ISO certified manufacturing.
  • —Stability: Supplied in a stable, lyophilized form for consistent results.
  • —Documentation: Full Certificate of Analysis (COA) included with every batch.
Research Focus
  • —Telomerase Activation: Induction of telomerase enzyme activity and telomere elongation.
  • —Cellular Senescence: Studies on bypassing the Hayflick limit in fibroblast models.
  • —Circadian Rhythms: Research into the regulation of melatonin synthesis in the pineal gland.
  • —Genomic Integrity: Investigating the reduction of chromosomal aberrations and DNA damage.
  • —Immune Modulation: Studies on interleukin-2 (IL-2) production and T-cell function in aging models.
Published Research and Study Findings

Epithalon is one of the most widely cited "longevity" peptides in Russian gerontology. Research pioneered by Vladimir Khavinson suggests that Epithalon acts by binding to promoter regions of DNA, effectively "unlocking" genes that become silenced as cells age. Laboratory studies have demonstrated that Epithalon can stimulate telomerase activity, resulting in telomere lengthening in both normal and cancer cell lines (though the effects vary by model).

Additionally, preclinical trials in rodents have observed a reduction in spontaneous tumour incidence and an increase in mean lifespan, potentially through its combined antioxidant and neuroendocrine-normalizing effects.

NoteAll findings are derived from laboratory, animal, and non-clinical research settings.
Representative Scientific References
  • 1.Khavinson, V.K. et al., "Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells," Bulletin of Experimental Biology and Medicine, 2003.
  • 2.Anisimov, V.N. et al., "Effect of Epitalon on biomarkers of aging, life span and spontaneous tumor incidence in female Swiss-derived SHR mice," Biogerontology, 2003.
  • 3.Korkushko, O.V. et al., "Geroprotective effect of Epithalamin (pineal gland peptide preparation) in elderly patients with accelerated aging," Bulletin of Experimental Biology and Medicine, 2006.
  • 4.Sibarov, D.A. et al., "Epitalon influences the electrical activity of neurons in the rat cerebral cortex," Neuroscience and Behavioral Physiology, 2007.
Technical data
Specifications
Purity
≥99%, HPLC verified
Form
Lyophilised white powder
Molecular formula
C14H22N4O9
Molecular weight
390.35 g/mol
Sequence
Ala-Glu-Asp-Gly
SKU
SHP-EPITH-010
Research category
Cognitive
Storage
-20°C, protected from light and moisture
Reconstitution
Reconstitute with bacteriostatic water; swirl gently, do not shake
Research use
In-vitro laboratory research only. Not for human consumption.
Common questions
Frequently asked questions
Epithalon is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) derived from a natural pineal gland peptide. It is supplied as a lyophilised powder at ≥99% purity under GMP certification.
It is studied for telomerase activation, cellular senescence and replicative lifespan, circadian rhythm regulation, genomic integrity and immune modulation. Reported outcomes vary between experimental systems.
Epithalon is supplied at ≥99% purity, verified by HPLC with mass-spectrometry identity confirmation. Testing is carried out per batch rather than per product line, so the figures on your certificate of analysis relate to the exact lot in your vial.
Store the sealed vial at -20°C, protected from light and moisture. Once reconstituted, the solution should be kept refrigerated at 2-8°C, protected from light, and treated as a short-lived working preparation rather than a long-term stock.
Epithalon is supplied lyophilised. Reconstitute with bacteriostatic water; swirl gently, do not shake, and allow the powder to dissolve fully before use. Direct the solvent down the inside wall of the vial rather than onto the pellet, and record the volume used so working concentrations can be calculated. This applies to in-vitro laboratory work only.
Epithalon is studied for delaying the onset of senescence through telomerase activation and extended replicative lifespan. FOXO4-DRI is a senolytic that clears cells which have already become senescent. The two represent prevention and clearance as separate strategies.
Yes. A certificate of analysis covering HPLC purity and mass-spectrometry identity is available for every batch of Epithalon. Each vial carries a batch number on its label, and quoting that number lets us send you the certificate that matches the material you hold rather than a generic example.
Epithalon has the molecular formula C14H22N4O9 and a molecular weight of 390.35 g/mol. Those figures are stated on the certificate of analysis supplied with each batch and are the values researchers use when preparing molar calculations.
Epithalon ships from the UK to UK research addresses, with tracked dispatch and insulated packaging. It is sold for in-vitro laboratory research only: it is not a medicine, not a supplement, and not for human or veterinary consumption. Orders are accepted on the basis that the buyer is a qualified researcher.