HGH Fragment 176-191
HGH Fragment 176-191

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HGH Fragment 176-191

HGH Fragment 176-191
HGH Fragment 176-191
HGH Fragment 176-191
HGH Fragment 176-191
HGH Fragment 176-191
HGH Fragment 176-191

HGH Fragment 176-191

£17.00Sold out
Out of stock
Size
1
ABOUT THIS COMPOUND
Description

HGH Fragment 176-191 from Super Human Peptides UK is a synthetic peptide representing the terminal C-terminus end of the human growth hormone molecule. In laboratory research, this specific 16-amino acid sequence is studied for its potent lipolytic (fat-breaking) properties. Unlike the full-length growth hormone molecule, Fragment 176-191 is engineered to isolate the fat-metabolism effects of GH without triggering growth-promoting (mitogenic) activity or influencing insulin sensitivity.

Produced under GMP-compliant conditions and verified for 99% purity or higher, HGH Fragment 176-191 is a primary tool for investigating lipid oxidation and adipose tissue regulation.

WarningFor laboratory research use only. Not for human consumption.
Key Features
  • —High Purity: 99% purity or higher (verified by HPLC and MS analysis).
  • —Targeted Lipolytic Agent: Isolated C-terminus sequence of hGH.
  • —Non-Glycaemic: Studied for its ability to avoid the "diabetogenic" effects of full HGH.
  • —Quality Standard: GMP / ISO certified manufacturing.
  • —Documentation: Full Certificate of Analysis (COA) included.
Research Focus
  • —Lipolysis Mechanisms: Studies on the breakdown of triglycerides in adipocytes.
  • —Inhibition of Lipogenesis: Research into the peptide's ability to block the formation of new fatty acids.
  • —Energy Homeostasis: Investigating systemic fat oxidation and metabolic rate in animal models.
  • —Beta-3 Adrenergic Receptors: Research into the secondary pathways through which the fragment may influence thermogenesis.
  • —Comparison Studies: Evaluating the fragment against full-length HGH for metabolic efficiency and safety profiles.
Published Research and Study Findings

HGH Fragment 176-191 has been extensively documented for its ability to mimic the way natural growth hormone regulates fat metabolism. Research led by Ng et al. (2000) demonstrated that this specific fragment retains the ability of GH to reduce body fat in obese animal models while significantly reducing the risk of side effects like fluid retention and decreased glucose tolerance.

Laboratory studies have shown that the fragment works by stimulating the breakdown of fat (lipolysis) and inhibiting the transformation of non-fatty foods into body fat (lipogenesis). Furthermore, because it lacks the "growth" portion of the GH molecule (the N-terminus), it does not compete for the GH receptor in a way that would stimulate IGF-1 levels, making it a highly specific tool for metabolic researchers.

NoteAll findings are derived from laboratory and non-clinical research settings.
Representative Scientific References
  • 1.Ng, F.M. et al., "Metabolic studies of a synthetic lipolytic fragment of human growth hormone," Metabolism, 2000.
  • 2.Heffernan, M.A. et al., "The effects of human GH and its lipolytic fragment (AOD9604) on lipid metabolism," Endocrinology, 2001.
  • 3.Wu, Z. et al., "Stimulation of lipolysis by the C-terminal fragment of human growth hormone," Journal of Peptide Research, 2003.
  • 4.Stier, H. et al., "Safety and tolerability of the hGH fragment AOD9604," Journal of Endocrinology and Metabolism, 2013.
Technical data
Specifications
Purity
≥99%, HPLC verified
Form
Lyophilised white powder
Molecular formula
C78H123N23O23S2
Molecular weight
1815.1 g/mol
Sequence
Human growth hormone C-terminal fragment, residues 176-191
SKU
SHP-FRAG176-005
Research category
Metabolic
Storage
-20°C, protected from light
Reconstitution
Reconstitute with bacteriostatic water; swirl gently, do not shake
Research use
In-vitro laboratory research only. Not for human consumption.
Common questions
Frequently asked questions
HGH Fragment 176-191 is a synthetic 16-amino-acid peptide representing the C-terminus of human growth hormone, supplied lyophilised at ≥99% minimum purity.
It is investigated for lipolytic activity, lipogenesis inhibition and energy homeostasis, in models where the growth-promoting and insulin-sensitivity effects of the full hormone would confound the result.
HGH Fragment 176-191 is supplied at ≥99% purity, verified by HPLC with mass-spectrometry identity confirmation. Testing is carried out per batch rather than per product line, so the figures on your certificate of analysis relate to the exact lot in your vial.
Store the sealed vial at -20°C, protected from light. Once reconstituted, the solution should be kept refrigerated at 2-8°C, protected from light, and treated as a short-lived working preparation rather than a long-term stock.
HGH Fragment 176-191 is supplied lyophilised. Reconstitute with bacteriostatic water; swirl gently, do not shake, and allow the powder to dissolve fully before use. Direct the solvent down the inside wall of the vial rather than onto the pellet, and record the volume used so working concentrations can be calculated. This applies to in-vitro laboratory work only.
Both are C-terminal growth hormone fragments studied in the same lipolysis models. HGH Fragment 176-191 runs from residue 176 and weighs 1815.1 g/mol; AOD-9604 begins at 177 and weighs approximately 1812 g/mol. Researchers select between them when the exact fragment boundary is relevant to the question.
Yes. A certificate of analysis covering HPLC purity and mass-spectrometry identity is available for every batch of HGH Fragment 176-191. Each vial carries a batch number on its label, and quoting that number lets us send you the certificate that matches the material you hold rather than a generic example.
HGH Fragment 176-191 has the molecular formula C78H123N23O23S2 and a molecular weight of 1815.1 g/mol. Those figures are stated on the certificate of analysis supplied with each batch and are the values researchers use when preparing molar calculations.
HGH Fragment 176-191 ships from the UK to UK research addresses, with tracked dispatch and insulated packaging. It is sold for in-vitro laboratory research only: it is not a medicine, not a supplement, and not for human or veterinary consumption. Orders are accepted on the basis that the buyer is a qualified researcher.