Ipamorelin
Ipamorelin

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Ipamorelin

Ipamorelin
Ipamorelin
Ipamorelin
Ipamorelin
Ipamorelin
Ipamorelin

Ipamorelin

£15.00Sold out
Out of stock
Size
1
ABOUT THIS COMPOUND
Description

Ipamorelin from Super Human Peptides UK is a synthetic pentapeptide and a highly selective Growth Hormone-Releasing Peptide (GHRP). It acts as an agonist of the ghrelin/growth hormone secretagogue receptor (GHS-R). In laboratory research, Ipamorelin is widely considered one of the most refined and "cleanest" secretagogues available.

Unlike earlier generation peptides such as GHRP-6 or Hexarelin, researchers utilize Ipamorelin because it stimulates a significant, pulsatile release of growth hormone without simultaneously elevating cortisol, acetylcholine, or prolactin levels. Produced under GMP-compliant conditions and verified for 99% purity or higher, Ipamorelin provides an ideal model for studying the somatotropic axis without the interference of stress-hormone cascades.

WarningFor laboratory research use only. Not for human consumption.
Key Features
  • —High Selectivity: Stimulates GH release without cortisol or prolactin spikes.
  • —Maximum Purity: 99% purity or higher (verified by HPLC and MS analysis).
  • —No Appetite Stimulation: Does not induce the extreme hunger response often seen in other GHRPs.
  • —Quality Standard: GMP / ISO certified manufacturing.
Research Focus
  • —Selective GH Pulsatility: Measuring pituitary output without secondary stress-hormone interference.
  • —Bone Mineral Density: Preclinical models investigating the peptide's ability to increase bone formation rates.
  • —Lean Muscle Tissue Retention: Studies on nitrogen balance and protein synthesis during metabolic stress.
  • —Gastric Motility: Researching its mild prokinetic effects on the gastrointestinal tract in animal models.
  • —Gerontology and Anti-Aging: Exploring the restoration of natural GH pulses in aged animal models.
Published Research and Study Findings

Ipamorelin was first detailed in scientific literature by Raun et al. (1998) as the first highly selective growth hormone secretagogue. Laboratory studies have consistently demonstrated that while its GH-releasing potency is similar to GHRP-6, its lack of effect on ACTH and cortisol makes it unique.

This allows researchers to study the pure physiological effects of elevated growth hormone—such as increased bone density and muscle tissue repair—without the confounding variables introduced by elevated stress hormones. Furthermore, long-term animal studies indicate that Ipamorelin does not cause rapid receptor desensitization (down-regulation) to the same extent as Hexarelin. This makes it a preferred peptide for prolonged, multi-week research models focusing on steady, consistent somatotropic stimulation.

NoteAll findings are derived from laboratory and non-clinical research settings.
Representative Scientific References
  • 1.Raun, K. et al., "Ipamorelin, the first selective growth hormone secretagogue," European Journal of Endocrinology, 1998.
  • 2.Johansen, P.B. et al., "Ipamorelin, a new growth-hormone-releasing peptide, induces longitudinal bone growth in rats," Growth Hormone & IGF Research, 1999.
  • 3.Svensson, J. et al., "The GH secretagogues Ipamorelin and GHRP-6 increase bone mineral content in adult female rats," Journal of Endocrinology, 2000.
  • 4.Venkova, K. et al., "Efficacy of ipamorelin, a novel ghrelin mimetic, in a rodent model of postoperative ileus," Journal of Pharmacology and Experimental Therapeutics, 2009.
Technical data
Specifications
Purity
≥99%, HPLC verified
Form
Lyophilised white powder
Molecular formula
C38H49N9O5
Molecular weight
711.86 g/mol
SKU
SHP-IPAM-005
Research category
Secretagogues
Storage
-20°C, protected from light
Reconstitution
Reconstitute with bacteriostatic water; swirl gently, do not shake
Research use
In-vitro laboratory research only. Not for human consumption.
Common questions
Frequently asked questions
Ipamorelin is a synthetic pentapeptide that acts as a selective growth hormone secretagogue at the ghrelin receptor. It is supplied as a lyophilised white powder verified at ≥99% purity by HPLC and MS.
It is studied where selective growth hormone release is required without concurrent elevation of cortisol, prolactin or acetylcholine, making it a common control in comparative secretagogue work.
Ipamorelin is supplied at ≥99% purity, verified by HPLC with mass-spectrometry identity confirmation. Testing is carried out per batch rather than per product line, so the figures on your certificate of analysis relate to the exact lot in your vial.
Store the sealed vial at -20°C, protected from light. Once reconstituted, the solution should be kept refrigerated at 2-8°C, protected from light, and treated as a short-lived working preparation rather than a long-term stock.
Ipamorelin is supplied lyophilised. Reconstitute with bacteriostatic water; swirl gently, do not shake, and allow the powder to dissolve fully before use. Direct the solvent down the inside wall of the vial rather than onto the pellet, and record the volume used so working concentrations can be calculated. This applies to in-vitro laboratory work only.
Hexarelin Acetate is described as one of the most potent secretagogues in the class and is used to probe the upper limits of pituitary output and receptor desensitisation. Ipamorelin produces a smaller but far more selective response. Where potency is the variable of interest, researchers use Hexarelin; where selectivity is, they use Ipamorelin.
Yes. A certificate of analysis covering HPLC purity and mass-spectrometry identity is available for every batch of Ipamorelin. Each vial carries a batch number on its label, and quoting that number lets us send you the certificate that matches the material you hold rather than a generic example.
Ipamorelin has the molecular formula C38H49N9O5 and a molecular weight of 711.86 g/mol. Those figures are stated on the certificate of analysis supplied with each batch and are the values researchers use when preparing molar calculations.
Ipamorelin ships from the UK to UK research addresses, with tracked dispatch and insulated packaging. It is sold for in-vitro laboratory research only: it is not a medicine, not a supplement, and not for human or veterinary consumption. Orders are accepted on the basis that the buyer is a qualified researcher.